Methods of treating at least one condition chosen from pain, inflammation, andfever in a critically ill patient inneed thereof, comprising administering to the critically ill patient anintravenous pharmaceutical composition comprisingibuprofen using a first dosage regimen, wherein the first dosage regimenproduces a first pharmacokinetic profile in critically ill patientsthat is about equivalent to a second pharmacokinetic profile produced byadministration of the intravenous pharmaceuticalcomposition using a second dosage regimen of ibuprofen to non- critically illpatients, wherein the at least one condition of the criticallyill patient is thereby treated.
