The present invention relates to a pharmaceutical composition for inhibiting the recurrence or metastasis of cancer. According to the present invention, there is provided a pharmaceutical composition for inhibiting the recurrence or metastasis of cancer, comprising a 2-deoxy-D-glucose (hereinafter referred to as 2-DG) inhibited the growth of cancer stem cells and inhibited cancer metastasis, which were previously unknown through inhibition of mammosphere formation and inhibition of EMT. The inhibitory effect of 2-DG on the drug for treating diabetic neuropathy or its pharmaceutically acceptable salt It was confirmed that the combined use of the active ingredients alone can inhibit cancer metastasis and cancer recurrence to a much greater extent than the conventional cancer alone. Therefore, when the pharmaceutical composition according to the present invention is used, it is possible to exhibit substantially more excellent effects while reducing the content of each active ingredient, thereby enabling more effective treatment while reducing adverse effects due to drug overdose and pharmacological action It becomes. In addition, it is expected to be more synergistic when combined with chemotherapeutic agents that have been shown to be resistant. Therefore, the pharmaceutical composition for inhibiting recurrence or metastasis of cancer according to the present invention can be very useful for treating and preventing metastasis or recurrence of various cancer diseases.본 발명은 암의 재발 또는 전이를 억제하기 위한 약제학적 조성물에 관한 것으로, 본 발명에 따라, 2-데옥시-D-글루코오스 (2-Deoxy-D-glucose, 이하 2-DG)의 유방암 줄기세포(mammosphere) 형성 억제 및 EMT의 억제를 통하여 그 동안 알려지지 않았던 암 줄기 세포의 증식 억제 및 암 전이 억제 효과를 확인하였으며, 비구아니드 계열 당뇨병 치료제 약물 또는 그의 약제학적으로 허용 가능한 염과 2-DG의 병용처리를 통하여 기존 각각의 활성 성분만을 사용하였을 경우와 비교하여 암 전이 억제 및 암 재발을 훨씬 감소시켜, 동일 함량을 기준으로 훨씬 우수한 암 전이 및 재발 억제 효과를 나타낼 수 있음을 확인하였다. 따라서, 본 발명에 따른 약제학적 조성물을 사용할 경우, 각 활성 성분의 함량을 줄이면서도 실질적으로 더욱 뛰어난 효과를 나타낼 수 있게 되어 약물 과용에 따른 부작용 및 약리작용에 따른 부작용을 감소시키면서 보다 효과적인 치료가 가능해진다. 더불어, 내성을 보였던
