Primary cultured adipocytes for gene therapy

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专利权人:

エーザイ・アール・アンド・ディー・マネジメント株式会社

发明人:

伊藤 昌史,齋藤 康

申请号：

JP2007299377

公开号：

JP4879867B2

申请日:

2007.11.19

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

<；P>；PROBLEM TO BE SOLVED: To provide cells suitable for gene therapy which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy, relating to primary cultured adipocytes for gene therapy, which stably hold a foreign gene encoding a protein that is secreted outside of the cell. <；P>；SOLUTION: Foreign genes retroviral vectors is transferred into primary cultured adipocytes, which are suitable for ex vivo gene therapy； can be easily collected and implanted； and can be removed after implantation, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. <；P>；COPYRIGHT: (C)2008,JPO&INPIT

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