The present invention relates to a compound according to formula I,wherein X, A, G, E, R1, R2, R3are as shown herein and pharmaceutically acceptable salts, hydrates, N-oxides or solvates hereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.本發明係關於一種式I之化合物其中X、A、G、E、R1、R2、R3係如本文所示;及其醫藥上可接受之鹽、水合物、N-氧化物或溶劑合物。本發明進一步係關於用於治療之該等化合物、包含該等化合物之醫藥組合物、使用該等化合物治療疾病(例如,皮膚疾病)之方法、及該等化合物在製造藥物中之用途。
