Michael Sekar,Felix Theeuwes,Keith E Branham,John Gibson,James Matriano,Whitney Moro,John Tipton,William Van Osdol,Su Il Yum
申请号:
US15887916
公开号:
US20180256727A1
申请日:
2018.02.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure generally provides complexes including a pharmaceutically active agent and a functionalized polymer, wherein the functionalized polymer includes repeat units, the repeat units including ionizable repeat units having at least one ionizable side group and/or ionizable end group, a plurality of the at least one ionizable groups forming non-covalent bonds with the pharmaceutically active agent. Polymers which may be used to form such complexes as well as methods of making and using the complexes and related compositions are also provided.