Juergen Dedio;Stephen J. Shimshock;Sven Grueneberg;Aleksandra Weichsel;Rosy Sher;Raymond W. Kosley, Jr.;Carolina L. Lanter;Werngard Czechtizky;Holger Heitsch;Hui Li;Stephanie Hachtel
发明人:
Stephanie Hachtel,Juergen Dedio,Holger Heitsch,Werngard Czechtizky,Sven Grueneberg,Stephen J. Shimshock,Raymond W. Kosley, Jr.,Carolina L. Lanter,Hui Li,Rosy Sher,Aleksandra Weichsel
申请号：
US13079522
公开号：
US08283479B2
申请日:
2011.04.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to compounds of the formula I:in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
