A method of forming a multielectrode array includes forming an alignment plate having at least two openings, forming an array bottom plate having at least two openings corresponding to the at least two openings of the alignment plate, temporarily fixing the array bottom plate to the alignment plate, inserting one or more probes or array sub-assemblies into the at least two openings, fixing the probes or array sub-assemblies to the array bottom plate, and removing the array bottom plate from the alignment plate to form a multielectrode array.