A novel maize variety designated PHVZS and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHVZS with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHVZS through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHVZS or a locus conversion of PHVZS with another maize variety.