THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;NIPPON ZOKI PHARMACEUTICAL CO., LTD.
发明人:
Ekihiro SEKI,Koichi MASUDA,Mitsuru NAIKI
申请号：
US15502358
公开号：
US20170224738A1
申请日:
2015.08.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
An object of the present invention is to provide a protective method for liver comprising the administration of an extract from inflamed tissues inoculated with vaccinia virus to a patient who needs the treatment and to provide a liver protective agent, etc. where such an extract is an active ingredient. In the present invention, it has been recognized that, in hepatocytes, activation of NF-B, expression of NF-B target genes, activation of JNK, apoptosis and fat accumulation can be inhibited or suppressed. The agent containing the extract as an active ingredient is a drug exhibiting less adverse action and high safety. Accordingly, the present invention provides very useful protective method for liver and liver protecting agent.
