Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof

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专利权人:

发明人:

Niels-Bjarne Woods,Roger Ronn,Carolina Guibentif

申请号：

US13706067

公开号：

US09428732B2

申请日:

2012.12.05

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Compositions and methods that employ various combinations of such factors as retinoic acid signaling inhibitors, antioxidants, BMP4, VEGF, prostaglandin E2 pathway stimulants, TPO, SCF, FLT-3, EPO, TGFβ1, p38 MAPK inhibitors, beta adrenergic receptor agonists, cell cycle inhibitors, RXR agonists, Cripto, and chromatin remodelers to drive differentiation of pluripotent stem cells towards primitive blood cells. Uses of such primitive blood cells are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/