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POLYPEPTIDE STRUCTURAL MOTIFS ASSOCIATED WITH CELL SIGNALING ACTIVITY
专利权人:
ATYR PHARMA; INC.
发明人:
GREENE, LESLIE, ANN
申请号:
EP10746935
公开号:
EP2403864A4
申请日:
2010.02.26
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Isolated polypeptides comprising or consisting essentially of specific structural motifs (e.g., three β-sheets and two α-helices) are provided, wherein the polypeptides exhibit at least one cell signaling and/or other non-canonical activity of biological relevance. Also provided are polynucleotides encoding such polypeptides, binding agents that bind such polypeptides, analogs, variants and fragments of such polypeptides, etc., as well as compositions and methods of identifying and using any of the foregoing.
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