Quantitative analysis of a tissue sample includes carrying out a ploidy measurement on a plurality of nuclei of the sample to determine the ploidy type of a sample and also carrying out a stroma measurement on a section to determine the stroma type of a sample. The ploidy type, e.g. diploid or non-diploid, and the stroma type, high or low stroma, give an improved patient survival estimate than the ploidy type alone.
