Malinin, Vladimir,Boni, Lawrence T.,Li, Xingong,Miller, Brian S.
申请号：
AU2006270008
公开号：
AU2006270008B2
申请日:
2006.07.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Provided are lipid antiinfective formulations substantially free of anioniclipids with a lipid to antiinfective ratio is about 1 :1 to about 4:1, and a meanaverage diameter of less than about 1 μm. Also provided is a method of preparinga lipid antiinfective formulation comprising an infusion process. Also providedare lipid antiinfective formulations wherein the lipid to drug ratio is about1 : 1 or less, about 0.75:1 or less, or about 0.50:1 or less prepared by an in linefusion process. The present invention also relates to a method of treating a patientwith a pulmonary infection comprising administering to the patient a therapeuticallyeffective amount of a lipid antiinfective formulation of the present invention.The present invention also relates to a method of treating a patient for cysticfibrosis comprising administering to the patient a therapeutically effectiveamount of a lipid antiinfective formulation of the present invention.
