The Board of Trustees of the Leland Stanford Junior University
发明人:
Jie Liu,Ronald Levy,Ravindra Majeti
申请号:
US15303720
公开号:
US10040862B2
申请日:
2015.04.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Humanized or chimeric anti-CD99 monoclonal antibodies are provided. The antibodies bind to and neutralize human CD99, and find use in various therapeutic methods. Embodiments of the invention include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the humanized or chimeric anti-CD99 monoclonal antibodies; and cell lines that produce these monoclonal antibodies. Also provided are amino acid sequences of the antibodies.