Michael Gruss;Stefan Schunk;Saskia Zemolka;Derek Saunders;Heinz Graubaum
发明人:
Stefan Schunk,Saskia Zemolka,Derek Saunders,Michael Gruss,Heinz Graubaum
申请号：
US12545461
公开号：
US08404740B2
申请日:
2009.08.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Spirocyclic cyclohexane compounds corresponding to formula IIn which R1, R2, R3 and R5 through R10 and X have defined meanings, a process for their preparation, pharmaceutical compositions containing such compounds, and the use of such spirocyclic cyclohexane compounds in the treatment and/or inhibition of pain and other conditions mediated by the ORL-1 or the μ-opioid receptor.
