5,6-Busaryl-2-pyridine carboxamide derivatives, their preparation, their therapeutic application as urotensin ii receptor antagonists

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专利权人:

SANOFI-AVENTIS

发明人:

JEAN-MICHEL ALTENBURGER,VALÉRIE FOSSEY,DANIEL GALTIER,FRÉDÉRIC PETIT

申请号：

BRPI0907719

公开号：

BRPI0907719A2

申请日:

2009.02.05

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention is directed to compounds of the general formula: as well as pharmaceutical compositions thereof. The invention is also directed to their therapeutic use as urotensin II receptor antagonists, e.g., in the treatment of cardiac, coronary, and central nervous system disorders. In particular embodiments, the invention relates to 5,6-bisaryl-2-pyridinecarboxamides, to their preparation and to their therapeutic use as urotensin II receptor antagonists.

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