The present disclosure provides a waterproof housing for wearable device, including a housing. The housing includes a first surface and a second surface opposite to the first surface. A first opening formed by an inward depression of the first surface, a second opening formed by an inward depression of the second surface. A first transparent layer is sealed at the first opening so as to expose the screen display of the wearable device. The second transparent layer is sealed at the second opening so as to realize the sensor detection of the wearable device. The present disclosure can better protect wearable device without affecting the health data detection of users by wearable device.