Methods for the production of protein containing free cysteine residues

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专利权人:

BOLDER BIOTECHNOLOGY INC.

发明人:

GEORGE N. COX,DANIEL H. DOHERTY,MARY S. ROSENDAHL

申请号：

BR0008759

公开号：

BR0008759B1

申请日:

2000.01.14

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention relates to novel methods of making soluble proteins having free cysteines in which a host cell is exposed to a cysteine blocking agent. The soluble proteins produced by the methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form pegylated proteins.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/