A driver assembly with a rotatable and interchangeable cannulated driver shaft for drilling a variety of fasteners. The driver assembly includes an elongated body having a proximal end and a distal end with a first channel extending from the distal end into the elongated body and a second channel extending from a first side of the elongated body into the elongated body. The driver assembly also includes a locking mechanism connected within the elongated body. The locking mechanism is rotatable between a first configuration and a second configuration. A cannulated driver shaft is removably attached to the locking mechanism and is rotatable between the first configuration and the second configuration via the locking mechanism.
