ALLERGEN-BINDING IGE MONOCLONAL ANTIBODIES AND METHOD FOR PREPARING HYPOALLERGENS

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专利权人:

VALTION TEKNILLINEN TUTKIMUSKESKUS

发明人:

JYLHA, SIRPA,NIEMI, MERJA,ROUVINEN, JUHA,LAUKKANEN, MARJA-LEENA,TAKKINEN, KRISTIINA,SODERLUND, HANS,MAKINEN-KILJUNEN, SOILI,HAAHTELA, TARI

申请号：

NZ57806808

公开号：

NZ578068A

申请日:

2008.01.29

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is human IgE antibodies and derivatives thereof, which bind non-continuous planar allergenic epitope, such as in â-lactoglobulin, with high affinity and specificity. The present invention also relates to processes for making and engineering such allergen binding monoclonal antibodies and to methods for using these antibodies and derivatives thereof in the field of immunodiagnostics and immunotherapy.

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