KUMOH NATIONAL INSTITUTE OF TECHNOLOGY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
KWON, OH HYEONG,권오형,LEE, MIN YOUNG,이민영,LEE, JAE BAEK,이재백,PARK, WON HO,박원호,CHO, DONG HWAN,조동환,KWON, OH HYEONGKR,LEE, MIN YOUNGKR,LEE, JAE BAEKKR,PARK, WON HOKR,CHO, DONG HWANKR
申请号：
KR1020140167367
公开号：
KR1016262200000B1
申请日:
2014.11.27
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a film-type anti-adhesion membrane produced by irradiating electronic beams onto the surface of a film uniformly mixed with silk fibroin and biodegradable synthetic polymer material, and a method for producing the same. The film-type anti-adhesion membrane according to the present invention has alleviated adhesion with respect to tissue and organs which has been a problem of a conventional anti-adhesion agent, and has improved flexibility, biocompatibility, and biodegradability. The film-type anti-adhesion membrane has a nano-fiber structure, so the penetration and movement of cells are blocked. Accordingly, an anti-adhesion function is excellent, and wound healing may be promoted. The film-type anti-adhesion membrane may be conveniently operated without being torn or broken down even when being folded or rolled, and may be operated or moved by a small operation tool. Thus, the film-type anti-adhesion membrane may be conveniently used and easily applied to various surgical operations. Also, in vivo decomposition and absorption thereof are possible, and complete in vitro discharge thereof is possible after a wound is healed. Moreover, an in vivo foreign material reaction may be minimized.본 발명은 견 피브로인과 생분해성 합성고분자물질을 균일하게 혼합한 필름의 표면을 전자빔 조사처리한 필름형 유착방지막 및 그 제조방법에 관한 것으로, 본 발명의 필름형 유착방지막은 종래 유착방지제의 문제점이었던 조직 및 장기에 대한 부착성, 유연성, 생체적합성, 생분해성 등을 개선하였고 나노섬유구조를 가져 세포의 침투 및 이동을 차단함으로써 유착방지능이 우수하고 상처의 치유를 촉진할 수 있고, 접거나 말아도 찢어지거나 부서지지 않고 조작이 간편하고 작은 수술 도구에 의한 조작이나 이동이 가능하므로 사용이 편리하고 다양한 외과 수술에 적용이 용이하며, 체내에서 분해 및 흡수가 가능하고, 상처 치유 후 체외로의 완전한 배출이 가능하며, 체내 이물반응을 최소화할 수 있다.
