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Control of biofouling in implantable biosensors
专利权人:
Fotios Papadimitrakopoulos;Santhisagar Vaddiraju
发明人:
Fotios Papadimitrakopoulos,Santhisagar Vaddiraju
申请号:
US13586436
公开号:
US09101301B2
申请日:
2012.08.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed herein is a device comprising a biosensor having disposed upon it a coating; the coating comprising a polymer matrix; where the polymer matrix is operative to facilitate the inwards and outwards diffusion of analytes and byproducts to and from the sensing element of the biosensor; and a sacrificial moiety; the sacrificial moiety being dispersed in the polymer matrix, where the sacrificial moiety erodes with time and increases the porosity of the polymer matrix thus offsetting decreases in analyte permeability as a result of biofouling.
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