COMBINATION THERAPIES TARGETING MITOCHONDRIA FOR CANCER THERAPY

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专利权人:

发明人:

申请号：

EP15786476.0

公开号：

EP3137117A4

申请日:

2015.05.01

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Pharmaceutical compositions for the treatment of cancer are provided. In one embodiment the composition comprises Gamitrinib and a P13K inhibitor selected from PX-866, AZD6482, LY294002. BEZ235, GSK458, GDCO941, ZSTK474, BKM120 and GSK2636771B. Methods of treating cancer are also provided. The present invention is based in part on the inventors discovery that combination therapy that targets mitochondria eliminates tumor adaptation induced by P13K inhibition, and improves clinical outcome in cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/