您的位置: 首页 > 农业专利 > 详情页

Using Benzimidazole or Indole compounds with a 1,2-diazole group to Inhibit Alpha-Synuclein Toxicity
专利权人:
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
发明人:
LINDQUIST, SUSAN L
申请号:
NZ58843105
公开号:
NZ588431A
申请日:
2005.09.16
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound of formula (V) where the substituents are as disclosed in the description. Also disclosed is the use of a compound of formula (V) in the manufacture of a medicament for inhibiting or preventing alpha-synuclein toxicity and/or fibril formation, inhibiting or preventing alpha-synuclein fibril growth, and/or causing disassembly, disruption, and/or disaggregation of alpha-synuclein fibrils and a-synuclein-associated protein deposits. Examples of compound of formula (V) include N-[1-(1H-benzimidazol-2-yl)-3-methyl-1H-pyrazol-5-yl]-4-chlorobenzamide and Ethyl{ [1-(1H-benzimidazol-2-yl)-3-methyl-1H-pyrazol-5-yl]amino} (oxo)acetate. Further disclosed is a composition comprising a compound of formula (V).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充