At least the activator of 1 kinds (excluding terubinahuin,), at least the volatile solvent of 1 kinds, at least the membrane formation component of 1 kinds and the composition for new section in order to deal with the obstacle of the nail and the skin which at least include the phosphatide of 1 kinds, treatment method of obstacle of these manufacturing methods and the nail and the skin. It follows to the application of the composition and the evaporation of the volatile solvent, the composition, as contained the activator (plural yeses) web size, causes the membrane which possesses structure.少なくとも1種の活性剤(テルビナフィンを除く)、少なくとも1種の揮発性溶媒、少なくとも1種の膜形成成分および少なくとも1種のリン脂質を含む爪および皮膚の障害を処置するための新規な局所用組成物、これらの調製方法ならびに爪および皮膚の障害の処置方法。組成物の適用および揮発性溶媒の蒸発に続き、組成物は、活性剤(複数可)を含有するウエブ様構造を有する膜を生じる。