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Rsv mucosal vaccine
专利权人:
国立大学法人徳島大学
发明人:
木戸 博,水野 大,上田 博嗣,吉川 浩司,大隅 恵介,山本 信行,周藤 健治
申请号:
JP2013531356
公开号:
JP6085886B2
申请日:
2012.08.29
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
A composition comprising the following composition: an AD vehicle including a synthetic peptide and a lipid, wherein the synthetic peptide includes the amino acid sequence KnLm (wherein n is 4 to 8 and m is 11 to 20), a carboxylvinyl polymer and an RSV antigen. The composition has an antibody producing ability which is further higher than that of a conventional mucosal vaccine, hence capable of exerting excellent anti-virus antigen-specific IgA antibody- and IgG antibody-inducing effect in the nasal wash and the serum, respectively, even with an extremely small quantity of an RSV antigen.
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