University of Pittsburgh-of the Commonwealth System of Higher Education
发明人:
Vorp, David A.,Soletti, Lorenzo,El-Kurdi, Mohammed,Stankus, John J.,Wagner, William R.,Hong, Yi
申请号:
AU2008210523
公开号:
AU2008210523B2
申请日:
2008.01.30
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
A tubular tissue graft device is provided comprising a tubular tissue and a restrictivefiber matrix of a bioerodible polymer about a circumference of the tubular tissue.The matrix may be electrospun onto the tubular tissue. In one embodiment, thetubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft,for example and without limitation, in a coronary artery bypass procedure. Alsoprovided is method of preparing a tubular graft comprising depositing a fibermatrix of a bioerodible polymer about a perimeter of a tubular tissue to producea tubular tissue graft device. A cardiac bypass method comprising bypassinga coronary artery with a tubular tissue graft device comprising a vein and a restrictivefiber matrix of a bioerodible polymer about a circumference of the vein also isprovided.