Described here are devices, methods, and kits for deployment of tissue anchors.In some variations, the devices described here comprise a shaft defining a lumenfor housing at least one anchor therein (the anchor having an eyelet) and a mechanismfor deploying the anchor distally from the lumen, wherein the inner diameterof the lumen is the same size or smaller than the diameter of the eyelet of the anchorto be disposed therein when the anchor is in an expanded configuration. In somevariations, the methods comprise loading an anchor within a lumen of a shaft (wherethe anchor comprises an eyelet and the shaft has a slot therethrough), passinga linking member through the slot and through the eyelet of the anchor, and deployingthe anchor. Other methods comprise loading an anchor within a lumen of a shaft,and deploying the anchor distally from the lumen.