Pharmaceutical compositions comprising peptide antagonists of vascular endothelial growth factor

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专利权人:

Michael Klagsbrun;Shay Soker

发明人:

Michael Klagsbrun,Shay Soker

申请号：

US13365373

公开号：

US08889620B2

申请日:

2012.02.03

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO: 1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO: 2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.

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