A blood purification apparatus and a blood purification system that is operable with increased ease even if a blood purifier requires special treatment conditions and operational settings is used. A blood purification apparatus includes a blood purifier for giving blood purification treatment by purifying blood of a patient; and a control device that executes, in accordance with preset treatment conditions and/or operational settings, an operation for performing the blood purification treatment or an operation associated with the blood purification treatment. The blood purification apparatus includes a registering device that is capable of registering, in advance, the treatment conditions and/or operational settings corresponding to a performance, characteristic, or function of the blood purifier; and a changing device that is capable of changing the treatment conditions and/or operational settings to the treatment conditions and/or operational settings registered by the registering device, in accordance with the blood purifier to be used in the blood purification treatment.