Shalwitz, Robert,Gardner, Joseph H.,Janusz, John M.
申请号：
AU2012268400
公开号：
AU2012268400A1
申请日:
2012.06.05
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
Disclosed herein is {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and the ester and amide prodrugs thereof, that can stabilize hypoxia inducible factor-2 alpha (HIF-2a) and thereby provide a method for treating cancer. Further disclosed are compositions which comprise {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and/or a prodrug thereof which can be used to treat cancer.
