INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
发明人:
HICKEY, ROBERT, J.,MALKAS, LINDA H.
申请号：
EP12800330
公开号：
EP2688566A4
申请日:
2012.03.21
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention described herein pertains to anticancer therapeutic agents that exhibit preferential cytotoxicity to malignant cells that express a cancer specific isoform of proliferating cell nuclear antigen (caPCNA) compared to cytotoxicity to comparable non-malignant cells, pharmaceutical compositions comprising the agents, and their use in cancer therapy.
