The invention refers to the substituted oxopiridine derivatives and the process for preparing these derivatives, as well as their use in the development of drugs for the treatment and / or prevention of diseases, especially cardiovascular diseases, preferably thrombosis or thrombotic disorders, edema and eye diseases.La invencion se refiere a derivados de oxopiridina sustituidos y a procesos para su preparacion, y tambien a su uso para preparar medicamentos para el tratamiento y/o profilaxis de enfermedades, en particular enfermedades cardiovasculares, preferentemente trastornos tromboticos o tromboembolicos, y edemas, y tambien trastornos oftalmicos.