Préparation du sel de maléate de neratinibe et son utilisation

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专利权人:

Wyeth LLC

发明人:

申请号：

EP12172411.6

公开号：

EP2537843A3

申请日:

2008.10.16

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy]anilino}-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.

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中国工程科技知识中心

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http://www.ckcest.cn/home/