OXVIG CLAUS,MIKKELSEN JAKOB HAUGE,JEPSEN MALENE RUNGE
申请号：
IN10426/DELNP/2015
公开号：
IN2015DN10426A
申请日:
2015.11.12
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
A method is provided of decreasing or increasing the activity of a Pappalysin polypeptide by decreasing or increasing the level of interacting Pappalysin and stanniocalcin polypeptides. A method is also provided of preventing treating or ameliorating a clinical condition in a mammalian subject such as a human being said method comprising administering to said mammalian subject such as human being an effective amount of a stanniocalcin polypeptide. Moreover a method is provided of preventing treating or ameliorating a clinical condition in a mammalian subject such as a human being said method comprising administering to said mammalian subject such as human being an effective amount of an agent capable of antagonizing interaction of a stanniocalcin polypeptide with a Pappalysin polypeptide.
