Methods and systems for identifying epileptogenic regions of the brain and locating seizure foci can use only interictal EEG data. These methods and systems enable a physician to locate seizure foci without having to wait for a patient to experience a seizure and have it recorded. A network causality analysis can be applied to the interictal EEG data to determine the causal nodes, the nodes influenced by the causal nodes and the causal connection or link between the nodes. The most influential causal nodes can be ranked and used to generate a map of causal links in the brain networks to accelerate the identification of the epileptogenic regions of the brain and the location seizure focus.
