methods of predicting the reaction of patients suffering from an inflammatory disorder, predicting the ability of patients to react, identifying patients suffering from an inflammatory disorder and its treatment, use of kits and kits
biomarkers are provided that predict the ability to react to beta7 integrin antagonists, including antibody to integrin subunit antibodies and methods of use of such biomarkers. In addition, methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, are provided. Methods of using these predictive biomarkers are also provided for the treatment of inflammatory bowel disease, including ulcerative colitis and crohn's disease.são fornecidos biomarcadores que preveem a capacidade de reação a antagonistas de integrina beta7, incluindo anticorpos de subunidade de antibeta7 integrina e métodos de uso desses biomarcadores. além disso, são fornecidos métodos de tratamento de distúrbios inflamatórios gastrointestinais tais como doenças intestinais inflamatórias, incluindo colite ulcerativa e mal de crohn. também são fornecidos métodos de uso desses biomarcadores de previsão para o tratamento de doenças intestinais inflamatórias, incluindo colite ulcerativa e mal de crohn.
