A resettable dosing mechanism comprises a dose button (66, 102) and a dial grip (52, 104) operatively coupled to the dose button (66, 102). A spindle (64) acts on a bung of a cartridge (25) and a driver (55) is operatively coupled between the dose button (66, 102) and the spindle (64). During an injection of the dose, the dose button (66, 102) moves in an axial direction to cause the spindle (64) to administer the dose. During resetting of the dose setting mechanism, the spindle (64) is retracted back into the dose setting mechanism. An advantageous resetting mechanism is described.