The present invention relates to antibodies that specifically bind to T-cell immunoglobulin domain and mucin domain 3 (Tim-3). The anti-Tim-3 antibodies can be used to treat, prevent or diagnose immune, cancerous, infectious diseases or other pathological disorders that may be modulated by Tim-3-mediated functions.本發明涉及特異性結合T細胞免疫球蛋白結構域和粘液素結構域3 (Tim-3)的抗體。抗Tim-3抗體可用於治療、預防或診斷免疫疾病、癌性疾病、感染性疾病或可通過Tim-3介導的功能調節的其他病理病症。