KYOCERA MEDICAL CORPORATION;THE UNIVERSITY OF TOKYO
发明人:
申请号:
EP08865567.5
公开号:
EP2233159B1
申请日:
2008.12.19
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An object is to provide a medical device having excellent antithrombotic and sliding characteristics, which can exert a cell adhesion inhibitory effect. A medical device comprising: a substrate capable of forming hydroxyl groups; and a biocompatible material layer laminated on the substrate at an appropriate position, wherein the hydroxyl groups are formed on a surface of the substrate at least at a required position by a surface treatment, while the biocompatible material layer is formed from a polymer containing phosphorylcholine groups, and wherein the substrate and the biocompatible material layer are joined via a binder layer formed from silica being covalently bonded with the hydroxyl groups and the biocompatible material, respectively.