Jerome I. Rotter,Kent D. Taylor,Stephan R. Targan,Talin Haritunians,Dermot P. McGovern,Xiuqing Guo
申请号:
US13140874
公开号:
US20120053131A1
申请日:
2009.12.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are methods of predicting the development of medically refractory ulcerative colitis (MR-UC) in a patient In one embodiment, disclosed is a method of prognosing ulcerative colitis in an individual by determining the presence or absence of one or more risk variants, where the presence of one or more risk variants is indicative of a severe and/or aggressive form of ulcerative colitis. In another embodiment, the severe form of ulcerative colitis is indicative of MR-UC.