Joycelyn Entwistle;Denis Georges Bosc;Glen Christopher MacDonald;Nicholas Ronald Glover;Jeannick Cizeau;Francina C. Chahal
发明人:
Nicholas Ronald Glover,Glen Christopher MacDonald,Joycelyn Entwistle,Jeannick Cizeau,Denis Georges Bosc,Francina C. Chahal
申请号:
US11570198
公开号:
US08383117B2
申请日:
2005.06.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a tumor specific antibody. In addition, the invention provides tumor-specific antibodies and immunoconjugates comprising the tumor-specific antibody attached to a toxin or label, and methods and uses thereof. The invention also relates to diagnostic methods and kits using the tumor-specific antibodies of the invention.