您的位置: 首页 > 农业专利 > 详情页

HUMAN ANTIBODIES BINDING CXCR4 AND APPLICATIONS THEREOF
专利权人:
L.L.C.;E. R. Squibb & Sons
发明人:
KUHNE, Michelle,BRAMS, Peter,TANAMACHI, Dawn M.,KORMAN, Alan,CARDARELLI, Josephine M.
申请号:
DK12155398
公开号:
DK2486941T3
申请日:
2007.10.01
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present disclosure provides isolated monoclonal antibodies that specifically bind to CXCR4 with high affinity, particularly human monoclonal antibodies. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for detecting CXCR4, as well as methods for treating various cancers, inflammatory disorders and HIV infection using an anti-CXCR4 antibody of this disclosure.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充