BEN DROR GAI,벤 드로르, 가이,PLATT DORIT,플랫, 도릿,FARKASH ORLY,파카쉬, 오를리,ZUABI RASSAN,주아비, 라싼,BAR ON ZOHAR,바-온, 조하르,SHULMAN AVIDOR,슐만, 아비도르,PELLED DORI,펠드, 도리,RICHTER YAEL,리히터, 야엘
申请号:
KR1020117001752
公开号:
KR1014681910000B1
申请日:
2009.06.24
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
This invention provides a preparation comprising serine glycerophospholipids which comprise a mixture of serine glycerophospholipids comprising eicosapentaenoic acid (EPA) and serine glycerophospholipids comprising docosahexaenoic acid (DHA), wherein each such serine glycerophospholipid comprising EPA and each such serine glycerophospholipid comprising DHA has the formula (I): wherein R″ is serine; wherein one of R or R′ is acyl EPA or acyl DHA and the other of R or R′ is hydrogen or an acyl group; wherein the combined amount of EPA and DHA present in such mixture of serine glycerophospholipids constitutes 10-50% by weight of the total fatty acids content of the serine glycerophospholipids in said preparation; and wherein the mixture is not identical to naturally occurring human or mammalian brain PS.본 명세서에 기재된 발명은 LA, 리놀렌산(알파-리놀렌산, 감마-리놀렌산), DHA 및 에이코사펜타에노일(EPA)의 특정 함량 및 특정 컨쥬게이션 패턴을 지니는, 예컨대, 지질의 상이한 공급원을 이용하는 비-포유동물 유래 세린 글라이세로인지질 컨쥬게이트의 혼합물을 포함하는 제제 및 그의 용도를 제공한다.