RADIO-FREQUENCY ELECTRICAL MEMBRANE BREAKDOWN FOR THE TREATMENT OF HIGH RISK AND RECURRENT PROSTATE CANCER, UNRESECTABLE PANCREATIC CANCER, TUMORS OF THE BREAST, MELANOMA OR OTHER SKIN MALIGNANCIES, SARCOMA, SOFT TISSUE TUMORS, DUCTAL CARCINOMA, NEOPLASIA, AND INTRA AND EXTRA LUMINAL ABNORMAL TISSUE
ONIK, Gary, M.,MIESSAU, James, A.,BOSTWICK, David, G.
申请号：
USUS2016/015944
公开号：
WO2016/123608A2
申请日:
2016.02.01
申请国别(地区):
WO
年份:
2016
代理人:
摘要：
An imaging, guidance, planning and treatment system integrated into a single unit or assembly of components, and a method for using same, that can be safely and effectively deployed to treat prostate cancer, unresectable pancreatic cancer, tumors of the breast or soft tissue, including those located in the head, neck, central nervous system or brain, melanoma, ductal carcinoma, neoplasia, or intra and extra luminal abnormal tissue. The system utilizes the novel process of Radio-Frequency Electrical Membrane Breakdown ("EΜΒ" or "RFEMB") to destroy the cellular membranes of unwanted or cancerous tissue without denaturing the intra- cellular contents of the cells comprising the tissue, thereby ablating it and exposing tumor antigens and oilier intra-cellular components which can have an immunologic effect on local or distant cancerous tissue., with or without the addition of immunologic adjuvant, drugs., agents, or materials. The system preferably comprises at least one EMB treatment probe (20), at least one trackable biopsy needle (200), at least one trackable anesthesia needle (300), and at least one controller unit for at least partially automating the treatment process.Système de guidage, dimagerie, de planification et de traitement intégré dans une unité simple ou un ensemble de composants, et procédé dutilisation de ce dernier, qui peut être déployé de manière sûre et efficace pour traiter le cancer de la prostate, le cancer du pancréas ne pouvant pas subir de résection, les tumeurs du sein ou de tissu mou, y compris ceux situés dans la tête, le cou, le système nerveux central ou le cerveau, un mélanome, un carcinome intracanalaire, une néoplasie ou un tissu anormal intra- ou extra-luminal. Le système utilise le nouveau processus de Rupture de Membrane Électrique par Radio-Fréquence ("EΜΒ" ou "RFEMB") pour détruire les membranes cellulaires du tissu cancéreux ou indésirable sans dénaturer le contenu intracellulaire des cellules comprenant le tissu, ce qui permet
