The Government of the United States; as represented by the Secretary of the Army
发明人:
Jay Hooper
申请号：
US16553556
公开号：
US20200102576A1
申请日:
2019.08.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention contemplates a new synthetic, codon-optimized Sin Nombre virus (SNV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The SNV ORF was cloned into a plasmid to form the first stable recombinant SNV full-length M gene that elicits neutralizing antibodies. The gene can be engineered into a vaccine system, and is useful to protect mammals against infection with Sin Nombre virus.
