This invention relates to a modular, scalable fogponic plant growth system for growing plants individually with roots physically and fluidly isolated from one another. A high-pressure fluid delivery system operates above 150 psi and is configured for fluidly connecting at least one spray nozzle positioned within each root enclosure to simultaneously deliver fluid to the roots of each plant within a zone of root enclosures. A passive drain system continuously removes any unabsorbed fluid, such that the roots of each and every plant are physically and fluidly isolated from one another.