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Неинвазивный способ комплексного анализа реологических свойств крови in vivo
专利权人:
Ermak Elena Mikhajlovna
发明人:
Ermak Elena Mikhajlovna,Ермак Елена Михайловна
申请号:
RU2015145937
公开号:
RU0002625281C2
申请日:
2015.10.26
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
FIELD: medicine.SUBSTANCE: in the zone of interest, the flow of blood through the vessel is probed with pulses of ultrasonic oscillations in the energy colour Doppler coding mode. The diameter d of the vessel, the thickness of the blood flow boundary layer, the area of the blood flow boundary layer, the area of axial blood flow, the cardiac contractions frequency are determined and parameters characterizing the blood rheological properties are calculated based on the obtained data: blood kinematic viscosityν, the Womersley number α, parameter α2, ε flow structure coefficient. The peak systolic velocity Vps of axial blood flow and the mean maximum velocity Vm of axial flow of blood are determined, the inter-intimal diameter of the vessel and the Reynolds number Re, shear rate V, and shear voltage τ are calculated based on these parameters. Intubation is carried out with a traffic intensity distribution map over the flow section and the following is further determined using the measurements: area Sos of the axial flow into the systole, area Sns of the flow into the systole, area Sod of the axial flow into the diastole, area Snd of the flow into the diastole, area Sδs into the systole, area Sδd into the diastole, systole time ts, diastole time td, heart cycle time t and the following is calculated from the obtained data: averaged thickness δxs of the boundary layer into the systole (cm) according to the formula: δxs=Sδs/[√π*(√Sns+√Sos)], where Sδs is the area of the boundary layer into the systole, Sns is the flow area into the systole, Sos is the axial flow area into the systole averaged thickness δxd of the boundary layer into the diastole (cm) according to the formula: δxd=Sδd/[√π*(√Snd+√Sod)], where Sδd is the boundary layer area into the diastole, Snd is the flow area into the diastole, Sod-ω is angular velocity (c-1) νs - blood kinematic viscosity into the systole (cSt) according to the formula: νs=ωδxs2 d - blood kinematic viscosity into the diastole (cSt) accor
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