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TARGETED DISRUPTION OF T CELL RECEPTOR GENES USING ENGINEERED ZINC FINGER PROTEIN NUCLEASES
- 专利权人:
- Sangamo Therapeutics, Inc.;Ospedale San Raffaele srl
- 发明人:
- Philip D. Gregory,Michael C. Holmes,David Paschon,Lei Zhang,Maria Chiara Bonini,Pietro Genovese,Zulma Magnani,Sara Mastaglio,Luigi Naldini
- 申请号:
- US15936210
- 公开号:
- US20180214485A1
- 申请日:
- 2018.03.26
- 申请国别(地区):
- US
- 年份:
- 2018
- 代理人:
- 摘要:
- Disclosed herein are methods and compositions for modifying TCR genes, using nucleases (zinc finger nucleases or TAL nucleases) to modify TCR genes.
- 来源网站:
- 中国工程科技知识中心
- 来源网址:
- http://www.ckcest.cn/home/