Qingqi Chen,Jonathan Daniel Heller,Rocio Alejandra Lopez,Amanda Jean Morris
申请号：
US12443926
公开号：
US08232277B2
申请日:
2007.10.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to nordihydroguaiaretic acid derivative compounds, namely, butane bridge modified nordihydroguaiaretic acid (NDGA) compounds and butane bridge modified tetra-O-substituted NDGA compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, metabolic diseases, such as diabetes and hypertension, or a proliferative disease, such as diverse types of cancers.
